Chemotherapy for Retinoblastoma


Review Article

Author Details : Rajarathna Thangavel, Hakan Demirci

Volume : 2, Issue : 4, Year : 2016

Article Page : 222-226


Suggest article by email

Get Permission

Abstract

Retinoblastoma is the most common primary malignant intraocular tumor of childhood. It has a mortality close to 60% in the developing world. With early diagnosis and treatment, survival rates could be high as 95%. Management of Retinoblastoma has undergone a paradigm change in the past two decades with globe salvage becoming the goal of treatment. Safety and efficacy of chemotherapeutic agents combined with their targeted delivery has increased the success rates of tumor control. This article reviews the treatment strategies using different routes of drug delivery to contain ocular and extraocular retinoblastoma, the risks and benefits and future of chemotherapy.

Keywords: Retinoblastoma, Chemotherapy, Intra-arterial melphalan, IAC, Intravitreal melphalan, Periocular cisplatin, VEC regimen

 


How to cite : Thangavel R, Demirci H, Chemotherapy for Retinoblastoma. IP Int J Ocul Oncol Oculoplasty 2016;2(4):222-226


This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.







View Article

PDF File  


Copyright permission

Get article permission for commercial use

Downlaod

PDF File    






Article Access statistics

Viewed: 1331

PDF Downloaded: 588