Cyanoacrylate glue: An emerging alternative for sealing of corneal perforation

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Original Article

Author Details : Dipti Wahi*, Vanshika Khanna, Ram Kumar

Volume : 10, Issue : 2, Year : 2024

Article Page : 85-90

https://doi.org/10.18231/j.ijooo.2024.017

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Abstract

Background: Maintaining corneal wound integrity is an important goal in corneal perforations resulting from either traumatic or non- traumatic etiology. Tissue adhesives (TA’s) are group of synthetic or naturally occurring compounds, which helps in wound reconstruction and have emerged as alternatives to conventional sutures.
Aim: Our study aims to evaluate the efficacy N- butyl cyanoacrylate TA in corneal perforations following infectious keratitis by assessment of its morphological and functional outcome.
Materials and Methods: A prospective observational study conducted over a period of 6 months on 42 eyes of 42 patients with perforated corneal ulcer, fulfilling the inclusion criteria, presenting to our outpatient department. A standard technique was used to apply TA to the site of perforation under topical anaesthesia in all patients and they were followed-up for a period of 6 weeks. Data analysis was done using SPSS software (Version 22) and P value calculated by Pearson Chi-square test (Fisher exact test). P- value < 0> Results: Morphological outcome in this study showed statistically significant relationship with causative organism and size of the perforations (p<0> Conclusion: TA’s works well when the corneal perforation is <1>  
Keywords: Corneal perforation, Tissue adhesive, N­ butyl cyanoacrylate

How to cite : Wahi D, Khanna V, Kumar R, Cyanoacrylate glue: An emerging alternative for sealing of corneal perforation. IP Int J Ocul Oncol Oculoplasty 2024;10(2):85-90

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