Clinical presentations, epidemiology and management of COVID-19 associated Mucor mycosis in a tertiary care hospital in South India

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Original Article

Author Details : Madhusudhan C N, Raghavendra R, Nischala Balakrishna*, DN Prakash, K Satish

Volume : 9, Issue : 1, Year : 2023

Article Page : 7-15

https://doi.org/10.18231/j.ijooo.2023.002

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Abstract

Aims: To study the statistics of the epidemiology, co-morbidities, clinical presentations, management and prognosis of the study group.
Materials and Methods: This is a retrospective study conducted in a tertiary care hospital in South India, among 100 subjects, between May 2021 and August 2021 when the Mucor mycosis cases were frequently being diagnosed and treated amongst COVID-19 infected patients.
The results showed that 34.0% were between 51-60 years with 100% patients confirmed COVID positive through RTPCR tests. 86.0% had confirmed mucor on CT scan. 50.0% had both eyes vision of 6/60 on presentation. 67.% had periorbital swelling with 51% having prior co-morbidities.63.0% patients received tablet Posaconazole 30mg as medical treatment and 60.0% required no surgical management.10.0% required orbital exenteration and 21.0% required partial maxillectomy.2% experienced orbital apex syndrome as associated complications.97.0% were discharged post treatment with 3% mortality. There was a positive correlation of medical management with respect to anterior segment and posterior segment findings P<0 P=0.79. P=0.43.> Conclusion: This study shows that immune suppression is directly related to infectivity by mucor mycosis. In order to contain symptomatology and grave prognosis amongst patients, early diagnosis, affordable treatment and follow-up including patient education about the etiology and pathogenesis of the disease must be available.
 
Keywords: Mucor mycosis, Corona virus, Rhino­orbito­cerebral mucor mycosis, Black Fungus, Immune suppression

How to cite : Madhusudhan C N, Raghavendra R, Balakrishna N, Prakash D, Satish K, Clinical presentations, epidemiology and management of COVID-19 associated Mucor mycosis in a tertiary care hospital in South India. IP Int J Ocul Oncol Oculoplasty 2023;9(1):7-15

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