Maternal and Neonatal risk factors in retinopathy of prematurity: A study from coastal city in south India


Original Article

Author Details : Anupama B*, Rashmi Jain, Rashmi S, Vidya Hegde, Shyam Sudhir

Volume : 7, Issue : 3, Year : 2021

Article Page : 294-298

https://doi.org/10.18231/j.ijooo.2021.060



Suggest article by email

Get Permission

Abstract

Introduction: Preterm babies often suffer from various systemic illnesses and struggle for survival in the neonatal intensive care unit (NICU). These preterm babies are at risk of developing ROP which is a potentially blinding condition. The presence of predisposing maternal and neonatal factors contributes for the development of ROP. Determining the association of risk factors with the development of ROP is essential in improving the screening and management of ROP.
Aim: To determine maternal, neonatal risk factors and influence of retinal immaturity at first screening for development of ROP.
Settings and design: Prospective, observational study conducted at a level of 3 PICU & department of ophthalmology.
Methods and Materials: All the preterm infants with gestational age ? 37 weeks admitted in NICU were first screened by 2 to 3 weeks of chronological age and followed up till the completion of retinal vascularization and regression of ROP following treatment. The zone of retinal vascularization at first screening and various maternal and neonatal risk factors were noted.
Results: Out of 166 babies screened, 18.67% progressed to ROP. Of the 36 babies with immature retina 58% developed ROP, while 7.7% neonates with mature retina developed ROP. Gestational age, birth weight, retina immaturity, respiratory distress syndrome and anaemia of prematurity were statistically significant for ROP.
Statistical analysis: Descriptive statistics was used to identify the association of risk factors with the development of ROP. Each risk factor was analyzed by univariate & multivariate logistic regression.
Conclusions: Low birth weight, low gestational age, immature retina and neonatal risk factors have a significant influence on the development of ROP.
Key Messages: Low birth weight, low gestational age and retinal immaturity are important risk factors for Retinopathy of prematurity.

Keywords: Immature retina, Gestational age, Birth weight, Neonatal/maternal risk factors, Retinopathy of prematurity


How to cite : Anupama B, Jain R, Rashmi S, Hegde V, Sudhir S, Maternal and Neonatal risk factors in retinopathy of prematurity: A study from coastal city in south India. IP Int J Ocul Oncol Oculoplasty 2021;7(3):294-298


This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.







Article History

Received : 27-09-2021

Accepted : 06-10-2021


View Article

PDF File   Full Text Article


Copyright permission

Get article permission for commercial use

Downlaod

PDF File   XML File   ePub File


Digital Object Identifier (DOI)

Article DOI

https://doi.org/ 10.18231/j.ijooo.2021.060


Article Metrics






Article Access statistics

Viewed: 1357

PDF Downloaded: 501