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- DOI 10.18231/j.ijooo.v.11.i.2.4
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Ocular surface squamous neoplastic disease: A major review
Ocular surface squamous neoplasia (OSSN) has a varied presentation. The etiopathogenesis is still not clearly understood, although various factors such as exposure to UV rays, viral infections and chemical carcinogens have been implicated. The number of patients with human immunodeficiency virus has increased which is reflected in an increase of this tumor with a poorer prognosis. Anterior segment OCT and confocal microscopy have become powerful tools to aid the diagnosis of OSSN.
References
- Shields CL, Shields JA. Tumors of the conjunctiva and cornea. Surv Ophthalmol. 2004;49(1):3–24.
- Karp CL, Moore JK, Rosa RH Jr. Ocular surface squamous neoplasia. Surv Ophthalmol. 1999;44(1):65–91.
- Sun EC, Fears TR, Goedert JJ. Epidemiology of squamous cell conjunctival cancer. Cancer Epidemiol Biomarkers Prev. 1997;6(2):73–7.
- Newton R, Ziegler J, Ateenyi-Agaba C, Bousarghin L, Casabonne D, Beral V, et al. Risk factors for conjunctival squamous cell carcinoma in Uganda. Br J Cancer. 2002;87(3):301–8.
- McDonnell JM, Mayr AJ, Martin WJ. DNA of human papillomavirus type 16 in dysplastic and malignant lesions of the conjunctiva and cornea. N Engl J Med. 1989;320(22):1442–6.
- Guthoff R, Lieb WE, Strobel P, Zettl A. Exenteration of invasive conjunctival squamous cell carcinoma. Br J Ophthalmol. 2004;88(8):1093–4.
- Lee GA, Hirst LW. Ocular surface squamous neoplasia. Surv Ophthalmol. 1995;39(6):429–50.
- Gichuhi S, Sagoo MS, Weiss HA, Burton MJ. Epidemiology of ocular surface squamous neoplasia in Africa. Trop Med Int Health. 2013;18(12):1424–43.
- Saurabh K, Kaliki S, Mishra DK Batra J, Naik MN. OSSN in 200 patients: A case control study of immunosuppression resulting from human immunodeficiency virus versus immunocompetency. Ophthalmology. 2015;122(8):1688–94.
- Gyal JL, Rao VA, Srinivasan R, Agrawal K. Oculocutaneous manifestations in xeroderma pigmentosa. Br J Ophthalmol. 1994;78(4):295–7.
- Karp CL, Galor A, Chhabra S, Barnes SD, Alfonso EC. Subconjunctival/perilesional recombinant interferon alpha2b for ocular surface squamous neoplasia: a 10-year review. Ophthalmology. 2010;117(12):2241–6.
- Tunc M, Char DH, Crawford B, Miller T. Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases. Br J Ophthalmol. 1999;83(1):98–103.
- Nanji AA, Sayyad FE, Galor A, Dubovy S. High-Resolution Optical Coherence Tomography as an Adjunctive Tool in the Diagnosis of Corneal and Conjunctival Pathology. Ocul Surf. 2015;13(3):226–
- Nolan GR, Hirst LW, Bancroft BJ. Application of impression cytology to the diagnosis of ocular surface tumors. Cancer. 1994;74(3):788–94.
- Shields CL, Demirci H, Karatza EC, Shields JA. Clinical survey of 1643 conjunctival tumors. Ophthalmology. 2004;111(9):1747–54.
- McKelvie PA, Daniell M, McNab A, Loughnan M, Santamaria JD. Squamous cell carcinoma of the conjunctiva: a series of 26 cases. Br J Ophthalmol. 2002;86(2):168–73.
- Galor A, Karp CL, Chhabra S, Barnes S, Alfonso EC. Topical interferon alpha 2b eye-drops for treatment of ocular surface squamous neoplasia: a dose comparison study. Br J Ophthalmol. 2010 May;94(5):551-4.
- Frucht-Pery J, Rozenman Y, Pe'er J. Topical mitomycin C treatment for corneal intraepithelial neoplasia. Am J Ophthalmol. 1996;121(2):230–2.
- Midena E, Angeli CD, Valenti M, de Belvis V, Ghirlando A. Treatment of conjunctival squamous cell carcinoma with topical 5- fluorouracil. Br J Ophthalmol. 2000;84(3):268–72.
- Yeoh CHY, Jerome JRL, Lim BXH, Sundar G, Mehta JS, Chan ASY, et al The management of Ocular Surface Squamous Neoplasia Int J Mol Sci. 2022;24(1):713
How to Cite This Article
Vancouver
Sarasvady ., Prasanth HR. Ocular surface squamous neoplastic disease: A major review [Internet]. IP Int J Ocul Oncol Oculoplasty. 2025 [cited 2025 Oct 02];11(2):57-59. Available from: https://doi.org/10.18231/j.ijooo.v.11.i.2.4
APA
Sarasvady, .., Prasanth, H. R. (2025). Ocular surface squamous neoplastic disease: A major review. IP Int J Ocul Oncol Oculoplasty, 11(2), 57-59. https://doi.org/10.18231/j.ijooo.v.11.i.2.4
MLA
Sarasvady, ., Prasanth, Hannah Ranjee. "Ocular surface squamous neoplastic disease: A major review." IP Int J Ocul Oncol Oculoplasty, vol. 11, no. 2, 2025, pp. 57-59. https://doi.org/10.18231/j.ijooo.v.11.i.2.4
Chicago
Sarasvady, .., Prasanth, H. R.. "Ocular surface squamous neoplastic disease: A major review." IP Int J Ocul Oncol Oculoplasty 11, no. 2 (2025): 57-59. https://doi.org/10.18231/j.ijooo.v.11.i.2.4